417 research outputs found

    Performances of conformal and planar arrays

    Get PDF
    Static and dynamic deformations can have a severe impact on the performance of conformal antennas on aircrafts and other vehicles. Therefore it is essential to study the different deformation and vibration mechanisms and their influence on the antenna's radiation pattern. This presentation gives an overview of different approaches concerning electromagnetic modelling of array antennas and investigations on antenna deformations presented in the scope of TG20

    Developing a New Perspective of Wellington\u27s City and Harbour: A Camera Obscura Exhibition

    Get PDF
    The Museum of Wellington City & Sea wants to expand the new ways of seeing concept developed by the Wellington Museums Trust by installing a camera obscura exhibition. The goal of our project was to develop the supportive educational and interactive experiences and a marketing plan for a camera obscura exhibition at the Museum of Wellington City & Sea. We sought to accomplish this through interviewing museum staff, surveying and interviewing visitors, and building a camera obscura model to perform a formative analysis. Finally, we provided recommendations for a complete camera obscura exhibition including educational programmes, interactive supplemental material, and marketing strategies

    A Single-Site Mutant and Revertants Arising in Vivo Define Early Steps in the Pathogenesis of Venezuelan Equine Encephalitis Virus

    Get PDF
    The early stages of Venezuelan equine encephalitis virus (VEE) pathogenesis in the mouse model have been examined using a genetic approach. Disease progression of a molecularly cloned single-site mutant was compared with that of the parental virus to determine the step in the VEE pathogenetic sequence at which the mutant was blocked. Assuming that such a block constitutes a genetic screen, isolates from different tissues thought to be distal to the block in the VEE pathogenetic sequence were analyzed to determine the pathogenetic step at which revertants of the mutant were selected. Directed mutation and analysis of reversion in vivo provide two powerful genetic tools for the dissection of the wild-type VEE pathogenetic sequence. Virus from the parental virulent clone, V3000, first replicated in the draining lymph node after subcutaneous inoculation in the left rear footpad. Movement of a cloned avirulent mutant, V3010 (E2 76 Glu to Lys), to the draining lymph node was impaired, replication in the node was delayed, and spread beyond the draining lymph node was sporadic. Serum, contralateral lymph node, spleen, and brain isolates from V3010 inoculated animals were invariably revertant with respect to sequence at E2 76 and/or virulence in mice. Revertants isolated from serum and contralateral lymph node retained the V3010 E2 Lys 76 mutation but also contained a second-site mutation, Glu to Lys at E2 116. Modification of the V3010 clone by addition of the second-site mutation at E2 116 produced a virus that bypassed the V3010 block at the draining lymph node but that did not possess full wild-type capacity for replication in the central nervous system or for induction of mortality. A control construct containing only the E2 116 reverting mutation on the V3000 background was identical to V3000 in terms of early pathogenetic steps and virulence. Therefore, analysis of mutant replication and reversion in vivo suggested (1) that the earliest steps in VEE pathogenesis are transit to the draining lymph node and replication at that site, (2) that the mutation in V3010 impairs transit to the draining lymph node and blocks dissemination to other tissues, and (3) that reversion can overcome the block without restoring full virulence

    Simplified aortic cannulation (SAC) – a useful technique for neonates with small aortas

    Get PDF
    A simplified means of arterial cannulation for cardiopulmonary bypass in small neonates and those infants with diminutive aortas, or requiring reconstruction of the ascending aorta, is presented. It involves suturing a long 3.5 mm graft to the innominate artery and inserting the arterial cannula into the end of the graft. This technique improves exposure, thereby greatly simplifying many complex repairs, and may be used for initiation of ECMO or for hybrid procedures in the postoperative period
    corecore